Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in every living cell, essential for over 500 enzymatic reactions. It serves as the primary substrate for sirtuins (SIRT1-7) — the longevity-associated proteins that regulate DNA repair, inflammation, and circadian rhythm. NAD+ levels decline precipitously with age, and restoring them has been linked to improved mitochondrial function, enhanced cognitive performance, and extended healthspan in multiple model organisms.
Categories: Longevity, Mitochondrial Optimization
Tags: longevity, anti-aging, sirtuins, DNA repair, energy, coenzyme, NAD